PT-141 Overview

PT-141, also known as Bremelanotide, is a synthetic research peptide structurally related to α-MSH (alpha-melanocyte-stimulating hormone). It is commonly studied for its interaction with melanocortin receptors, particularly MC3R and MC4R, which are involved in a range of physiological processes in the central nervous system. PT-141 is of interest in laboratory research investigating neural pathways, receptor activity, and peptide signaling mechanisms.

Product Details

• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
• Molecular Formula: C50H68N14O10
• Molecular Weight: 1025.2 g/mol
• PubChem CID: 9941370
• CAS Number: 189691-06-3

Research Highlights

1. Melanocortin Receptor Studies: Frequently used to investigate melanocortin receptor MC3R and MC4R interactions and their influence on neuronal pathways in lab settings.
2. Peptide Signaling: PT-141 provides a model compound for studying peptide-receptor binding, intracellular signaling, and related neurochemical responses.
3. Neurochemical Research: Its structure and binding affinity make it suitable for central nervous system research, particularly in experimental models exploring non-hormonal pathways.
4. Exploratory Applications: Subject of research into behavior-related neuroreceptor studies involving arousal and response pathways under controlled scientific conditions.

Usage and Safety Information

This product is strictly intended for laboratory and research use only. It is not approved for human consumption or therapeutic application. All research involving PT-141 must follow institutional safety protocols and applicable regulations.