Tesamorelin Overview

Tesamorelin is a synthetic research peptide classified as a stabilized Growth Hormone Releasing Hormone (GHRH) analog. It incorporates a trans-3-hexenoic acid modification at the N-terminus, enhancing its stability and increasing resistance to enzymatic degradation. Tesamorelin is widely used in controlled laboratory environments to investigate GHRH receptor activation, growth hormone secretion pathways, peptide–receptor interactions, and metabolic signaling models.

Product Details

• Product Name: Tesamorelin
• Chemical Name: Stabilized Growth Hormone Releasing Factor (1-44)
• Molecular Formula: C221H366N72O67S
• Molecular Weight: 5135.77 g/mol
• CAS Number: 218949-48-5
• Sequence: trans-3-Hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Gln-Gln-Ala-Gly-Ala-NH₂
• Appearance: White to off-white lyophilized powder
• Purity: ≥ 98%
• Storage Conditions: Store in a cool, dry environment. Refrigeration recommended for extended stability.

Laboratory Notes

Tesamorelin is extensively used in laboratory research focused on GHRH receptor binding, growth hormone release kinetics, and the mapping of downstream metabolic signaling pathways. Its enhanced structural stability makes it valuable for in vitro studies exploring peptide longevity, receptor selectivity, and the modulation of GH–IGF signaling cascades. Researchers often employ Tesamorelin in endocrine pathway models requiring consistent and controlled stimulation.

Usage & Handling

For laboratory research use only. Not intended for human or animal consumption. All handling should comply with appropriate laboratory safety procedures and institutional guidelines.

Storage Guidelines

Store the lyophilized peptide in a tightly closed container, protected from moisture and light. Refrigeration at 2–8°C is recommended for long-term stability. Avoid repeated freeze–thaw cycles.

Disclaimer

This compound is provided exclusively for scientific research purposes. Sigma Peptides does not make or imply any claims relating to human or animal health. Not for diagnostic, therapeutic, or clinical use.