TB500 (Thymosin Beta-4) Overview

TB500, also known as Thymosin Beta-4, is a synthetic peptide fragment studied extensively in preclinical and in vitro models. It is a naturally occurring peptide found in a variety of tissues and is involved in cellular migration and actin-binding dynamics. Research into TB500 explores its structural properties and its potential influence on cytoskeletal organization and peptide transport mechanisms.

Product Details

• Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
• Molecular Formula: C212H350N56O78S
• Molar Mass: 4963.4408
• CAS Number: 77591-33-4
• PubChem: CID 16132341

Research Highlights

1. Actin-Binding Potential: TB500 has been studied for its ability to bind G-actin and regulate polymerization processes within cell cultures.
2. Peptide Transport Studies: Frequently used in models evaluating peptide uptake, bioavailability, and distribution in tissues.
3. Cellular Migration Pathways: Investigated for its potential role in modulating cellular locomotion and cytoskeletal dynamics in in vitro settings.
4. In Vitro Tissue Modeling: Often utilized in simulated tissue models assessing structural peptide behavior under stress and repair conditions.

Usage and Safety Information

This compound is strictly intended for laboratory research use only. It is not approved for human or veterinary consumption. All handling must follow appropriate laboratory safety protocols.