Ipamorelin Overview

Ipamorelin is a synthetic pentapeptide classified as a selective Growth Hormone Secretagogue (GHS) and ghrelin receptor (GHSR1a) agonist. It is widely used in controlled laboratory environments to investigate pituitary signaling, GH pulse modulation, peptide–receptor specificity, and intracellular pathways involving cAMP and calcium flux. Unlike earlier GHS-class peptides, Ipamorelin is valued for its high receptor selectivity, making it ideal for in vitro studies on targeted GH release without broad off-target stimulation.

Product Details

• Product Name: Ipamorelin
• Chemical Name: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
• Molecular Formula: C38H49N9O5
• Molecular Weight: 711.86 g/mol
• CAS Number: 170851-70-4
• Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
• Appearance: White to off-white lyophilized powder
• Purity: ≥ 98%
• Storage Conditions: Store in a cool, dry environment. Refrigeration recommended for extended stability.

Laboratory Notes

Ipamorelin is widely used in peptide-receptor interaction research due to its selective action on the ghrelin/GHSR1a receptor. It is commonly incorporated in experiments focused on pulsatile GH release, intracellular signaling cascades, calcium ion mobilization, and the study of GHSR-mediated endocrine pathways. Its limited off-target activity makes it ideal for controlled in vitro models requiring precise stimulation of GH secretagogue pathways.

Usage & Handling

For laboratory research use only. Not intended for human or animal consumption. All handling should comply with appropriate laboratory safety procedures and institutional guidelines.

Storage Guidelines

Store the lyophilized peptide in a tightly closed container, protected from moisture and light. Refrigeration at 2–8°C is recommended for long-term stability. Avoid repeated freeze–thaw cycles.

Disclaimer

This compound is provided exclusively for scientific research purposes. Sigma Peptides does not make or imply any claims relating to human or animal health. Not for diagnostic, therapeutic, or clinical use.